This series of calculators uses the principle of Hardy-Weinberg equilibrium to calculate various figures related to allele and / or genotype frequencies for autosomal variants. Use p,q CHWE: Genotypes to calculated expected genotype frequencies from known allele frequencies. Use p,q CHWE: Check to check whether or not observed genotype frequencies are consistent with Hardy-Weinberg expectations. Use p,q CHWE: p,q ​​to calculate expected allele and genotype frequencies for a biallelic variant based on a known genotype frequency. To calculate heterozygosity (H) and polymorphism information content (PIC) of variants / markers, use p,q CHWE: PolyPICker.​