This calculator uses the principle of Hardy-Weinberg equilibrium to calculate heterozygosity (H) and polymorphism information content (PIC) of up to five variants each with up to 20 alleles. This is especially useful for the selection of highly informative markers for use in family linkage studies. The calculation for PIC is based on the formula described by Botstein et al. (1980). Refer to usage notes for further information.​

polypicker_usage_notes.pdf
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