Calculators for Familial or Polygenic Hypercholesterolemia
Use LDL-C SNP Scorer to calculate 12-SNP LDL-C SNP scores according to Talmud et al. (2013). HyperLDL-C Sourcery allow users to undertake a risk calculation to determine the probability that hypercholesterolemia is due to various causes (i.e. monogenic or multi-factorial), given various factors, such as phenotype, family history, the presence of any potentially pathogenic variants in FH-related genes, and LDL-C SNP scores.