Calculators for Familial or Polygenic Hypercholesterolemia
LDL-C SNP Scorer can be used to calculate 12-SNP LDL-C SNP scores according to Talmud et al. (2013). LDL-C SNP Interpreter, currently under development, will allow users to undertake a risk calculation to determine the probability that hypercholesterolemia is due to various causes (i.e. monogenic or multi-factorial), given various factors, such as phenotype, family history, the presence of any potentially pathogenic variants in FH-related genes, and LDL-C SNP scores.