This simple calculator uses the principle of Hardy-Weinberg equilibrium to calculate expected allele and genotype frequencies for an autosomal biallelic variant from the known frequency of any one of the three possible genotypes. This is especially useful to calculate the carrier frequency of an autosomal recessive phenotype from its known prevalence, or to calculate prevalence from a known carrier frequency. Tip: Input the known genotype frequency either as a decimal (e.g. 0.001) or as a formula (e.g. =1/1000).
Please do not attempt to download this program. This program will not operate if downloaded.